Controlling Cellular Uptake of Nanoparticles with pH-Sensitive Polymers
نویسندگان
چکیده
منابع مشابه
Controlling Cellular Uptake of Nanoparticles with pH-Sensitive Polymers
The major challenge in cancer therapy is to efficiently translocate drug molecules into cancer tumors without doing any damage to healthy tissues. Since there exist pH gradients between tumor and normal tissues, pH-sensitive materials may have great potential to overcome such challenge. Here, we report one new type of pH-responsive drug delivery system where pH-sensitive polymers are introduced...
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متن کاملSupplementary Materials: Uptake of pH-Sensitive Gold Nanoparticles in Strong Polyelectrolyte Brushes
The mass of AuNP (mgold) in 1 mL AuNP suspension is (1.6 ± 0.4)×10−3 g, as derived by gravimetric analysis. In order to calculate the total amount of substance (ntotal) of AuNPs in 1 mL suspension, the total number of particles (Ntotal) in 1 mL AuNP suspension has to be calculated. This was done by estimating the mass of a single AuNP. Assuming a spherical shape and an uniform face centered cub...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2013
ISSN: 2045-2322
DOI: 10.1038/srep02804